An international research team co-led by Vanderbilt University Medical Center has revealed how variations in gene regulation in different cell types drive pulmonary fibrosis, a progressive respiratory disorder characterized by scarring and loss of functional lung tissue.

Anna Hemnes, MD, has been named director of the Division of Allergy, Pulmonary and Critical Care Medicine, physician-in-chief of the Vanderbilt Lung Institute and director of the Center for Lung Research.

Special Agent Adam Daniels celebrates ongoing recovery after gunshot causes traumatic brain injury; family’s gift will support care of others with similar injuries

John Koethe, MD, MSCI, associate professor of Medicine in the Division of Infectious Diseases at Vanderbilt University Medical Center, has been appointed director and principal investigator of the Tennessee Center for AIDS Research.

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health (NIH) to create the world’s first, integrated knowledge base of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

While immune checkpoint inhibitors that target the PD-1 molecule on T-cells have proven to be effective with many cancers, these immunotherapies have not worked for acute myeloid leukemia (AML), but new research has identified a “cousin” molecule as a potential therapeutic target for AML. 

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity.