Division of Diabetes Endocrinology and Metabolism

December 22, 2020

Pancreatlas provides access to complex images of the human pancreas

Images of cells and tissues are a critical part of biomedical research as they show which molecules or proteins are present and where these molecules are located in the tissue. Using increasingly sophisticated microscopes and imaging approaches, scientists can now look at more than 40 different molecules at once, an approach known as multi-plex imaging, where in the past they could only look at three or four molecules at a time.

By Jill Clendening
Katie Coate, PhD, left, Jeeyeon Cha, MD, PhD, and colleagues are working to understand the interaction of diabetes and COVID-19.
December 10, 2020

Study sheds light on diabetes and COVID interaction

COVID-19 has been linked to cases of new-onset diabetes, diabetes-related emergencies and a higher death rate among diabetes patients.

By Bill Snyder
November 17, 2020

A cohort for type 2 diabetes studies

A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs.

By Leigh MacMillan
Marcela Brissova, PhD, and MD/PhD student John “Jack” Walker are part of the research team that developed a pseudoislet system for integrated studies of human islet function.
July 30, 2020

Pseudoislet system expected to advance pancreas and diabetes research

The multicellular, 3-D structure of human pancreatic islets — the areas of the pancreas containing hormone-producing or endocrine cells — has presented challenges to researchers as they study and manipulate these cells’ function, but Vanderbilt University Medical Center researchers have now developed a pseudoislet system that allows for much easier study of islet function.

By Jill Clendening
August 15, 2019

Gannon named to new faculty development role

Maureen Gannon, PhD, has been named to the newly created role of Associate Dean for Faculty Development for Vanderbilt University School of Medicine.

By John Howser
Team members involved in the study include, from left, Melissa Hilmes, MD, Daniel Moore, MD, PhD, Alvin Powers, MD, Jon Williams, PhD, and Jack Virostko, PhD. (photo by Jessica Kimber)
April 25, 2019

Study expands insight on shrinking pancreas in type 1 diabetes

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) have discovered a progressive decline in pancreas volume over a one-year period in children and adolescents with newly diagnosed Type 1 diabetes.

By Jill Clendening
January 17, 2019

Study points to alternate therapy for rare form of diabetes

Vanderbilt University Medical Center researchers say an unexpected finding during the cellular analysis of human pancreatic tissue has revealed new information about a rare type of diabetes and underscores the importance of genetic testing for some individuals diagnosed with type 1 diabetes.
By Jill Clendening
November 29, 2018

Beta cell biomarker findings may speed diabetes research

Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding, reported this month in the journal Cell Metabolism, could lead to improved ways to study and treat diabetes.
By Bill Snyder
November 8, 2018

Vitamin C protects brain from seizures

Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.
By Nora Foegeding
September 13, 2018

First Islet Workshop draws international audience

More than 200 investigators from across the globe who specialize in islet biology, the study of hormone-producing cell clusters in the pancreas known as islets, recently gathered in Nashville to share knowledge and present the challenges and successes of their work during the first Islet Biology Workshop at Vanderbilt.
By Jill Clendening
March 6, 2018

Discovery by Vanderbilt-led group could lead to improved diabetes treatment

Vanderbilt investigators and colleagues around the country have made a major discovery that could lead to better ways to treat type 1 diabetes (T1D).
By Bill Snyder
December 1, 2017

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease

Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.
By VUMC News and Communications
November 9, 2017

New phenotyping program to bolster global diabetes research efforts

The use of human pancreatic islets to conduct diabetes-related research has greatly expanded in recent years, and a Human Islet Phenotyping Program (HIPP) at Vanderbilt University Medical Center has been established to provide important islet data to investigators worldwide.
By Jill Clendening
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