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Epithelial Biology Center Archives

Single-cell study of tumor samples

Oct. 26, 2016—A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer.

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Goldenring recognized for research mentorship efforts

Jun. 23, 2016—James Goldenring, M.D., Ph.D., co-director of the Epithelial Biology Center at Vanderbilt University Medical Center (VUMC), has received a Research Mentor Award from the American Gastroenterology Association Institute Council for “outstanding research mentorship.”

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Study suggests cancer’s ‘clock’ can be rewound

Mar. 17, 2016—Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented.

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Clinicians, researchers team to treat boy’s rare disorder

Mar. 3, 2016—Test after test failed to reveal why Denny Majano wasn’t gaining weight or why he suffered from severe, chronic diarrhea. At 5 weeks old, instead of gaining weight as newborns should, Denny had lost a pound since birth.

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DISSECTing cell signaling networks

Dec. 14, 2015—Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution.

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Bad “traffic” linked to cancer

Sep. 3, 2015—Understanding how signaling molecules are transported within and out of the cell may help to uncover the causes of certain cancers.

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Nutrient-absorbing surface’s assembly revealed: study

Apr. 17, 2014—Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.

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Defusing ‘C. diff’ infection

Nov. 8, 2013—Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. difficile toxin, TcdB, induces rapid cell death of human colon cell lines and pig colonic...

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Cell changes en route to stomach cancer

Sep. 26, 2013—Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.

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$5.2M NIH grant bolsters colorectal cancer research

Aug. 15, 2013—Robert Coffey Jr., M.D., Ingram Professor of Cancer Research at Vanderbilt University, has received a five-year, $5.2 million grant from the National Institutes of Health (NIH) to study the role of extracellular RNA (ex-RNA) in colorectal cancer.

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New ‘super’ microscopes sharpen cellular imaging

Jul. 11, 2013—Two new “super-resolution” optical microscopes have put Vanderbilt University Medical Center on the cutting edge of cellular imaging, and are giving researchers their first views of the cell at the molecular level.

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Disease linked to cell traffic jams

Jun. 20, 2013—Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.

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Recent Stories from VUMC News and Communications Publications

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