Eric Gamazon

July 8, 2024

GeneMAP discovery platform will help define functions for ‘orphan’ metabolic proteins 

The combination of genomics and metabolism identified a long-sought mitochondrial choline transporter.

By Leigh MacMillan
July 20, 2023

Predicting gene expression may speed discovery: study

Researchers at Vanderbilt University Medical Center and the University of Cambridge have developed a method of or predicting gene expression in hard-to-access tissues like the brain from more accessible tissues, including whole blood.

By Bill Snyder
May 9, 2023

Neural networks probe proteins

A machine learning method based on neural networks outperformed a mutational scanning model at identifying disease-causing mutations in an Alzheimer’s disease protein, suggesting the method could be useful for facilitating therapeutic design.

By Leigh MacMillan
December 8, 2022

Researchers develop framework for multiancestry genomic studies

Vanderbilt researchers have developed a framework for the analysis of multiancestry, large-scale genomic studies across multiple biobanks.

By Leigh MacMillan
October 21, 2021

Study links genetic variants, protein expression and human diseases

An international research team has developed a new resource that connects genetic variants and protein expression, which is expected to speed the identification of genes that cause disease — and point to novel treatment strategies.

By Leigh MacMillan
July 8, 2021

Genetics of hydrocephalus

Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition.

By Leigh MacMillan
October 22, 2020

New tool to probe genetic mechanisms of disease

Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases.
By Leigh MacMillan
September 10, 2020

Award supports integration of genomic data, electronic health records

Eric Gamazon, PhD, assistant professor of Medicine, has been awarded a $1.5 million grant from the National Human Genome Research Institute, part of the National Institutes of Health (NIH), to develop novel computational tools that integrate functional genomic data and electronic health records.
By Leigh MacMillan
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.
By Leigh MacMillan
September 19, 2019

Gamazon receives NIH Genomic Innovator Award

VUMC's Eric Gamazon is one of only six investigators to receive an inaugural Genomic Innovator Award from the National Human Genome Research Institute, part of the NIH.
By Leigh MacMillan
April 24, 2019

Study merges big data and zebrafish biology to reveal mechanisms of human disease

In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.
By Leigh MacMillan
October 11, 2018

Novel genetic study sheds new light on risk of heart attack

Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.
By Bill Snyder
July 26, 2018

Vanderbilt study links gene expression, disease association data

An international team of researchers has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.
By Leigh MacMillan
1 2