hypertension (high blood pressure)

October 21, 2024

Clue to salt-sensitive blood pressure found

Despite the well-established link between high salt intake and cardiovascular disease and stroke, the mechanism of SSBP is poorly understood, and it remains an untreatable cardiovascular risk with no widely available diagnostic tool.

By Bill Snyder
September 9, 2024

Peptide discovery could advance treatment of high blood pressure

VUMC researchers found that peptides modified by highly reactive compounds called isolevuglandins activated T cells and promoted hypertension in mice. Their first-ever isolation of such peptides is a step toward potentially intervening in this pathologic process.

By Bill Snyder
August 13, 2024

$3.4 million research grant targets risk of heart attack, stroke

Making innovative use of observational data, researchers hope to gain new understanding of patient risk and identify existing drugs to lower risk.

By Paul Govern
Three-dimensional imaging of kidney tubules (yellow and green noodle-like structures) under low potassium conditions, which puts the kidney into a state of metabolic overdrive and causes cardiovascular problems.
August 5, 2024

Low potassium ‘turns on’ kidney proximal tubule: study

A kidney protein that responds to low levels of blood potassium — which can cause high blood pressure and cardiovascular problems — may be a target for new therapeutics.

By Leigh MacMillan
(Adobe Stock)
July 24, 2024

Study links low-quality sleep with chronic disease

The research shows that by getting enough sleep and reducing variability around sleep onset and wake times, patients can reduce the incidence of chronic disease.

By Matt Batcheldor
(iStock image)
May 1, 2024

Study finds 500 new blood pressure genes

An analysis of the genomes of more than 1 million people of European ancestry, conducted by several of the world’s leading genomic centers, including Vanderbilt University Medical Center, has identified more than 2,000 independent genetic signals for blood pressure.

By Bill Snyder
November 13, 2023

Most can lower blood pressure by reducing salt, even those on BP drugs: study

New research shows nearly everyone can lower their blood pressure, even people currently on blood pressure- reducing drugs, by lowering their sodium intake.
By Bill Snyder
October 25, 2023

Study to explore link between salt taste sensitivity and salt intake, hypertension and genetic variations in individuals of African descent

A new study will explore the link between salt taste sensitivity and salt intake, blood pressure, hypertension, and genetic variations in individuals of African descent.
By VUMC News and Communications
June 26, 2023

Magnesium deficiency and blood pressure

Dietary magnesium depletion in a mouse model activated inflammatory pathways and molecules that promote hypertension, suggesting that increased magnesium consumption may be beneficial for reducing the prevalence of hypertension.
By Leigh MacMillan
April 24, 2023

Kenneth Reynolds weighed 780 lbs., and his body was shutting down. Vanderbilt Weight Loss Center gave him back his life.

Coming up: going fishing with his grandchildren
By Jill Clendening
March 16, 2023

Cardiovascular research pioneer Inagami mourned

Tadashi Inagami, PhD, DSc, Vanderbilt University Professor of Biochemistry, emeritus, who helped characterize the biochemical basis for hypertension, heart failure and vascular disease, died in Pittsburgh, Pennsylvania, March 13 after a brief illness. He was 92.
By Bill Snyder
March 2, 2023

Sex-specific regulation of kidney signals

Links between estrogen signaling and sodium excretion by the kidney could help explain a reduced risk of hypertension in females versus males.
By Kelsey Pinckard
January 19, 2023

Is drinking tea good for your gut?

Microbiome profiling of older Chinese adults showed that tea drinking changed the diversity and abundance of some bacteria in men but not women — effects that may contribute to a reduced risk of hypertension.
By Sarah E. Glass
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