inflammation

little girl using inhaler
January 4, 2018

Asthma study may point to potential new therapeutic approach

New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition.

By Leigh MacMillan
November 13, 2017

Salt, inflammation and hypertension

Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension.

By Leigh MacMillan
concept illustration of knee with pain radiating from it
November 1, 2017

Bioactive lipids and rheumatoid arthritis

An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease.

By Leigh MacMillan
October 12, 2017

A switch for autoimmunity

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.

By VUMC News and Communications
June 9, 2017

Flip side of gut protection

Vanderbilt investigators report that dysregulation of certain immune cells in the intestines may lead to inflammation and disease.

By Laura Daniel
x-ray of stomach
November 3, 2016

A DARPP role in gastric cancer

Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies.

By Sanjay Mishra
September 8, 2016

Going after the ‘heart attack gremlin’

A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target.
By Sanjay Mishra
March 22, 2016

New treatment for Crohn’s disease

A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease.
By Leigh MacMillan
March 9, 2016

Eye of a cytokine storm

A new animal model can be used to “dissect” the inflammatory response to infection.
By Bill Snyder
January 7, 2016

Immune tolerance in endothelial cells

Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.
By Leigh MacMillan
October 29, 2015

Inflammation, obesity and diabetes

Vanderbilt study adds to the mounting role for inflammatory signaling in obesity.
By Leigh MacMillan
October 2, 2015

The yin and yang of COX-2

New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.
By Sanjay Mishra
September 4, 2015

Vitamin C protects blood vessel lining

Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.
By Leigh MacMillan
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