JAMA Network Open (journal) Archive — Page 1 of 5

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September 14, 2026

How ‘mismatched donors’ are opening new doors for blood cancer patients

The ACCESS trial allowed mismatched, unrelated donors for blood cancer patients who didn’t have a perfect match for a stem cell transplant; the trial enrolled a more varied population of patients.

September 2, 2026

Millions get wrong genetic test, study finds

A study shows current testing is providing false reassurance about genetic disposition for a rare life-threatening drug reaction.

July 24, 2026

Study shows one-fifth of prescribed cancer drugs initially denied coverage in Medicare were overturned when reviewed

The most common reason for initial denials was “non-medically acceptable” indications, or drugs prescribed “off-label,” which means using a drug outside its formally approved indication.

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May 18, 2026

Study finds benefit in genotype-guided care for depression

Genetic variants known to slow or speed metabolism of drugs for depression and anxiety disorders are very common.

March 10, 2026

Loneliness is a critical step on the road to suicide: Study

Mental health treatment is often out of reach. A person-centered approach to reducing loneliness that helps people engage with others might be more feasible.

February 27, 2026

Demographic and histologic factors influence risk of colon polyp recurrence

Vanderbilt Health study supports shift toward dynamic surveillance that extends monitoring for patients with specific demographic and histologic risk profiles.