New England Journal of Medicine Archives
New procedure helps patients avoid leg amputation
Mar. 30, 2023—More than 75% of patients facing amputation from the most severe form of peripheral artery disease were able to keep their limb after an innovative treatment as part of a multicenter study published in the New England Journal of Medicine.
High-dose flu vaccine beneficial for pediatric stem cell transplant patients
Mar. 2, 2023—Vanderbilt was the lead site for an influenza vaccine study in pediatric allogeneic hematopoietic stem cell transplant recipients that may lead to a change in the current flu vaccine recommendations in this vulnerable population.
Aspirin’s effectiveness at preventing blood clots studied
Feb. 9, 2023—A Vanderbilt study found that aspirin is as effective as low molecular weight heparin at preventing hospital-acquired deep venous thromboembolism, or blood clots in the veins, for orthopaedic trauma patients.
Study of two sepsis interventions finds identical outcomes
Feb. 2, 2023—Vanderbilt University Medical Center had a leading role in a large national study designed to compare two early interventions in the treatment of patients with sepsis, the body’s severe response to an uncontrolled infection.
Study defines role of steroids in congenital heart disease surgery
Nov. 10, 2022—Steroids are commonly given to infants during open-heart surgery to reduce inflammation, but whether the drugs significantly improve patient outcomes has not been settled — until now.
Study finds Moderna’s COVID-19 vaccine safe and effective for young children
Nov. 4, 2022—A Vanderbilt study finds that Moderna’s COVID-19 vaccine is safe and effective in children 6 months to 5 years of age.
Vanderbilt study finds that the most common oxygen saturation targets for hospitalized patients appear equally safe and effective
Oct. 24, 2022—A Vanderbilt study looked at the oxygen saturation target that results in optimal outcomes — number of days alive and free of mechanical ventilation — in 2,500 critically ill adults receiving mechanical ventilation.
Study shows two vaccine doses for mothers eases COVID complications for infants
Jul. 6, 2022—Infants younger than 6 months were better protected from COVID-19 complications when mothers received two doses of the vaccine while pregnant, according to Vanderbilt researchers.
Research probes cause of acute flaccid myelitis in children
Jun. 8, 2022—Research that began at Vanderbilt University Medical Center has found evidence that a viral infection followed by a “robust” immune response is the cause of a polio-like paralyzing illness in children called acute flaccid myelitis (AFM).
VUMC-led study finds Moderna COVID vaccine safe and effective for children
May. 12, 2022— by Bill Snyder Moderna’s COVID-19 vaccine is safe and generates robust immune responses in children ages 6 to 11 years, a national clinical trial co-led by Vanderbilt University Medical Center vaccine expert C. Buddy Creech, MD, MPH, has found. The two-dose vaccine (given approximately one month apart) led to antibody responses in more than...
New study illustrates how much it would cost for cancer drugs covered under Medicare Part D
May. 10, 2022—A new study by Vanderbilt researchers highlights how some older Americans diagnosed with cancer can face unlimited out-of-pocket spending for prescription drugs under the current structure of the Medicare Part D benefit.
Study finds azithromycin use during RSV not useful in preventing recurrent wheezing, may cause harm
Feb. 28, 2022—Vanderbilt research on the impact of the antibiotic azithromycin during severe respiratory syncytial virus (RSV) bronchiolitis overwhelmingly support current national bronchiolitis guidelines, which recommend against antibiotics during acute bronchiolitis due to lack of effect on the acute illness.