The Kay Yow Cancer Fund, in partnership with the Women’s Basketball Coaches Association and The V Foundation for Cancer Research, has awarded a $100,000 ovarian cancer research grant to the Vanderbilt-Ingram Cancer Center.

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments.

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.