COVID alters respiratory microbiota
Apr. 25, 2023—COVID-19 infection alters the microbes of the upper respiratory tract for at least several weeks, and such disturbances could impact disease severity and be targets for therapeutic interventions.
New high-tech biobank safeguards critical specimens
Aug. 25, 2022—by Bill Snyder Vanderbilt University Medical Center has opened a state-of-the-art automated biobanking system that can store as many as 10 million biospecimens, including blood and body fluids, tissue, and genetic and protein material, at temperatures down to minus 80 degrees Celsius. The “BioStore” was purchased from its manufacturer, Massachusetts-based Azenta Life Sciences, with the...
Researchers discover how salt increases blood pressure
Aug. 17, 2022—A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.
‘Friendly’ bacteria may impact COVID severity
Mar. 11, 2021—The U.S. Centers for Disease Control and Prevention (CDC) has awarded Vanderbilt University Medical Center a two-year, $3.7-million contract to determine genetic and bacterial factors that may increase the risk for severe illness and death from COVID-19.
Study tracks genomics of lung tumor behavior
Apr. 9, 2020—A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors.
HDAC3 role in B-cell development
Aug. 3, 2017—The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.
Genotyping project to be an ‘engine of discovery’
Aug. 6, 2015—Vanderbilt University researchers next month will launch a major initiative to acquire “dense genotypes” from 100,000 individuals whose medical histories are known.
Core facilities key driver of VUMC research gains
Jan. 29, 2015—During the past five years, Vanderbilt University Medical Center has become a leader in “personalized medicine,” the use of genomic information to individualize patient care.
Apr. 25, 2013—Travis Clark, Ph.D., technical director of Sequencing in the VANTAGE core laboratories, shows a tour group how DNA fragments are loaded onto “flow cells” for reading by “next-generation” sequencing machines.
Study tracks genes involved in heart rhythm disorders
Feb. 7, 2013—A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm.
Genomic research gains ad-“vantage” with new resources
Nov. 1, 2012—Vanderbilt University Medical Center has stepped up its support of research aimed at cracking the mysteries of the genome, the master DNA code.