Thousands of Americans die each year during a dangerous two-minute procedure to insert a breathing tube. Now a Vanderbilt University Medical Center (VUMC) study in the New England Journal of Medicine (NEJM) is showing that using bag-mask ventilation, squeezing air from a bag into the mouth for 60 seconds to help patients’ breathing, improves outcomes and could potentially save lives.

Understanding how a bacterial protein that influences the risk of stomach cancer is produced could guide new strategies for treatment.

Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.

Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.

Using sophisticated gene sequencing and computing techniques, researchers at Vanderbilt University Medical Center and the San Diego Supercomputer Center have achieved a first-of-its-kind glimpse into how the body’s immune system gears up to fight off infection.

Some biomedical researchers may be unsure about routine electronic health record (EHR) data and how useful it ultimately may prove for drawing meaningful, actionable associations that warrant changes to clinical practice and lead to improved clinical outcomes.