Research

December 2, 2014

Lindquist named to receive Vanderbilt Prize in Biomedical Science

Susan Lindquist, Ph.D., a pioneer in the field of protein folding at the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, is the recipient of the 2014 Vanderbilt Prize in Biomedical Science, Vanderbilt University officials announced this week.

By Bill Snyder
November 26, 2014

New tools to probe manganese biology

Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

By Leigh MacMillan
November 21, 2014

Host sequesters zinc to control stomach bug

Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.

By Leigh MacMillan
Deciphering DNA code
November 20, 2014

Gene mutation linked to breast cancer therapy resistance

A group of Vanderbilt-led investigators has identified a new gene mutation that may explain why some breast cancer patients do not respond to anti-hormone therapy.

By VUMC News and Communications
November 20, 2014

Team finds drug repurposing signal in e-health records

With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increasing production.

By Paul Govern
November 7, 2014

Overactive stress response in obesity

An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial.

By VUMC News and Communications
October 16, 2014

Staph ‘gangs’ share nutrients during infection: study

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies.
By Leigh MacMillan
October 15, 2014

Antibiotics, fetal vessel defect linked

Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.
By VUMC News and Communications
September 25, 2014

A path to sarcoidosis treatment

Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis.
By VUMC News and Communications
September 16, 2014

Patient-derived stem cells shed light on pulmonary hypertension

Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies.
By Leigh MacMillan
September 4, 2014

Lung cancer study reveals new drug combination targets

A Vanderbilt lung cancer patient’s exceptional response to different types of therapies spurred research that suggests lung cancer patients with specific gene alterations may benefit from combination therapy that targets two different cancer pathways.
By VUMC News and Communications
August 21, 2014

Transfusions ease strokes for children with sickle cell

Vanderbilt-led research found regular blood transfusion therapy significantly reduces the recurrence of strokes in children with sickle cell anemia who have previously had "silent" strokes.
By Christina Echegaray
August 14, 2014

Team takes 4-D look at brain receptor’s role

Reporting last week in the journal Cell, researchers from Oregon Health and Science University, Harvard Medical School and Vanderbilt University describe the first “four-dimensional” picture of a brain receptor that plays a key role in learning and memory.
By Bill Snyder