Study examines HIV drug’s potential to treat Alzheimer’s

A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer’s disease.

New tool may speed antibody, vaccine research

Gregor Mendel would be proud

A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do.

Study reveals mysteries of critical brain receptor complex

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.

Genetic screen in worms reveals critical step in insulin synthesis

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.

Study finds ‘frozen’ fear response may underlie PTSD

To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed.