Research Archive — Page 98 of 139

Close-up of a mosquito with a swollen reddish abdomen feeding on human skin against a blurred green background.
January 23, 2020

Antibody isolated at VUMC found to halt dengue virus

Using part of an antibody isolated at Vanderbilt that “broadly neutralizes” the human dengue virus, biologists at the University of California San Diego and colleagues have disarmed the mosquito that transmits the disabling and potentially deadly tropical infection.

By Bill Snyder
Futuristic digital illustration of a human head and shoulders formed from glowing blue and pink pixels, overlaid with a microchip, circuit patterns, binary digits, and waveform graphics.
January 15, 2020

VUMC study to use artificial intelligence to explore suicide risk

Investigators will use computational methods to shed light on suicidal ideation and its relationship to attempted suicide, predict suicidal ideation and suicide attempt using routine electronic health records (EHRs) and explore the genetic underpinnings of both.

By Paul Govern
Side-by-side fluorescent microscopy comparison: larger, regularly shaped healthy cartilage cells on the left and smaller, irregularly shaped cells in the CATIFA model on the right, labeled “Healthy Cartilage Cells” and “CATIFA model Cartilage Cells.”
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

By Leigh MacMillan
Illustration of branching cream-colored blood vessels with blue and dark red channels, surrounded by green cell-like forms, small white microbes, and scattered particles on a reddish background.
January 13, 2020

Zinc uptake by a deadly pathogen

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.

By Leigh MacMillan
Illustration of a magnifying glass enlarging the porous internal structure of a bone, with a partial skeletal bone visible behind it.
January 10, 2020

Bone matrix changes during aging

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.

By Leigh MacMillan
Multi-panel molecular structure diagram showing a colored pore and prepore complex (a), with wireframe views of the pore (b) and prepore (c). Scale bars indicate 93 Å, 32 Å, and 98 Å.
January 10, 2020

Structural views of a C. diff toxin

D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.

By Leigh MacMillan