Parkinson’s disease

Neimat: Emotional disturbance is an overlooked symptom of Parkinson’s

Despite benefiting from dramatic improvements in movement after deep brain stimulation surgery, patients with Parkinson’s disease can be inadequately served when physicians and researchers focus only on its motor manifestations, says a Vanderbilt neurosurgeon.

Study sheds light on a ‘guardian’ protein of brain function

Mitochondria not only are the cell’s main power producers, they are also the chief cooks and bottle washers.

Copper toxicity and Parkinson’s

A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.

New tools to probe manganese biology

Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

colorful x-ray of brain

Team takes 4-D look at brain receptor’s role

Reporting last week in the journal Cell, researchers from Oregon Health and Science University, Harvard Medical School and Vanderbilt University describe the first “four-dimensional” picture of a brain receptor that plays a key role in learning and memory.

DBS for Parkinson’s trial moves to next level

A long-term Vanderbilt University Medical Center study of deep brain stimulation (DBS) in early-stage Parkinson’s disease has received approval from the Food and Drug Administration (FDA) to continue in a pivotal, phase III, large-scale safety and efficacy trial.

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