Immature nerves and neural precursor cells increase in density as a type of premalignant tumor in the pancreas progresses to invasive disease, suggesting that blocking these cells may arrest malignant progression.

A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought.

The number of sarcoma research studies that use the two largest U.S. cancer registries is increasing, but over one-third of studies that asked the same research question reported conflicting findings.

Vanderbilt researchers show that a TLR4 agonist improves lung immune response and survival in a mouse model of bacterial pneumonia, supporting the development of this drug to protect against pneumonia in hospitalized patients.

New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output.

Vanderbilt researchers describe a new mechanism for the most common form of lupus and suggest a new treatment approach to this autoimmune disease.