Leigh MacMillan

August 26, 2017

All over the Medical Center, and all over the world

When Debby Booth started college in the early 1970s, she didn’t want to be a nurse. That was something her older sister did.

By Leigh MacMillan
August 24, 2017

Grants bolster research on rare neurological disorder AHC

Kevin Ess, M.D., Ph.D., Gerald M. Fenichel Professor of Neurology, has received two grants from the Alternating Hemiplegia of Childhood Foundation (AHCF).

By Leigh MacMillan
August 21, 2017

Fatty acids and adenoma risk

Vanderbilt researchers have found that red blood cell membrane fatty acid content is associated with risk of having colorectal adenomas, with omega-6 fatty acids increasing and omega-3 fatty acids decreasing risk.

By Leigh MacMillan
colored representation of cells and glia
August 17, 2017

Discovery sheds light on protein key to nerve cells’ myelin sheath

Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.

By Leigh MacMillan
August 17, 2017

Block estrogen to treat lung disease

Based on findings from Vanderbilt investigators and others, clinical trials of estrogen inhibition for pulmonary arterial hypertension have recently been approved and funded by the National Institutes of Health.

By Leigh MacMillan
x-ray of stomach
August 8, 2017

Early drivers of gastric cancer

Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers.

By Leigh MacMillan
August 3, 2017

HDAC3 role in B-cell development

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.
By Leigh MacMillan
July 21, 2017

Probing the genetics of autoimmunity

Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.
By Leigh MacMillan
July 20, 2017

Drivers of breast cancer metastasis

Signaling through a complex of proteins called mTORC2 plays a role in breast cancer migration, invasion and metastasis, Vanderbilt researchers reported.
By Leigh MacMillan
July 5, 2017

Bile acids, microbiota and colon cancer

Bile acids produced by a western diet alter the composition of the gut microbiota and promote intestinal carcinogenesis.
By Leigh MacMillan
June 29, 2017

Team investigates antiviral that inhibits SARS, MERS

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.
By Leigh MacMillan
June 14, 2017

PET imaging to predict tumor response

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.
By Leigh MacMillan
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