Leigh MacMillan

August 9, 2013

‘Yo-yo dieting’ inflames fat tissue

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

By Leigh MacMillan
July 31, 2013

Factor’s role in long bone development

Insight into how the protein neurofibromin participates in the signaling pathway that produces the body’s long bones has implications for fracture healing in some patients.

By Leigh MacMillan
July 29, 2013

Motor protein revs up cell division

A motor protein that helps drive cell division may be a promising new target for cancer therapeutics.

By Leigh MacMillan
July 25, 2013

Visualizing data on network ‘maps’

The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification.

By Leigh MacMillan
July 17, 2013

Probing roles of a cell death protein

Vanderbilt researchers have discovered new roles for a protein involved in cell death processes that are activated to prevent tumor-causing DNA mutations.

By Leigh MacMillan
July 15, 2013

Defining patient retention

Vanderbilt researchers propose guidelines for defining patient retention in clinical studies – an important parameter that affects study conclusions and program evaluations.

By Leigh MacMillan
July 12, 2013

Methods for imaging myelin loss

Certain MRI metrics can be used to assess myelin loss in multiple sclerosis, which is important for planning and monitoring therapy.
By Leigh MacMillan
July 11, 2013

Model for MADD mitochondrial disease

A zebrafish model of a severe mitochondrial disease will be useful for developing new therapeutic approaches.
By Leigh MacMillan
June 26, 2013

Insights on glaucoma gene mutations

Glaucoma-causing mutations in the gene for myocilin reduce secretion of the protein into the aqueous humor, suggesting a new option for treatment.
By Leigh MacMillan
June 24, 2013

Predicting cancer’s response to therapy

Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding.
By Leigh MacMillan
June 21, 2013

Rhythm response tied to gene variant

A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder.
By Leigh MacMillan
June 20, 2013

Studies outline new model for staph bone infections

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.
By Leigh MacMillan
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