Aliquots - Research Briefs

HIV cell

New strategy to combat HIV

Inhibitors of the enzyme phospholipase D1 suppress the replication of HIV-1, Vanderbilt investigators have discovered.

A “CRISPR” way to study disease

Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases.

Preventing early pregnancy complications

The enzyme alkaline phosphatase may provide a new therapeutic option for women at high risk of pregnancy complications due to bacterial toxin exposure.

Tools for exploring ‘omics’ data

The NetGestalt computing portal integrates vast amounts of data to aid users in finding biologically and clinically relevant information.

Boosting cell-based heart repair

A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells.

Insights on lysosomal storage diseases

A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features.

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