Aliquots - Research Briefs

August 20, 2015

New therapeutic target for diabetes

The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.

By Leigh MacMillan
August 12, 2015

Origins of neuroblastoma

Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer.

By Leigh MacMillan
August 11, 2015

Drug combos enhance ovarian cancer cell death

Drugs that target DNA damage improve ovarian cancer cell response to platinum chemotherapies, suggesting new therapeutic opportunities.

By Leigh MacMillan
August 7, 2015

Bridging the antibiotic gap

Vanderbilt researchers have discovered how certain molecules with antibiotic properties are synthesized, findings that could lead to new drugs that overcome the increased antibiotic resistance in bacteria.

By Sanjay Mishra and Bill Snyder
August 6, 2015

Stomach cancer cues

Vanderbilt scientists have discovered a new molecular mechanism that promotes stomach cancer development, findings that could provide new opportunities for treatment.

By VUMC News and Communications
July 29, 2015

In a zebrafish’s eye

Vanderbilt investigators demonstrate that a certain eye lens protein is evolutionarily conserved between zebrafish and rat, suggesting that zebrafish can be used as a model system to understand eye lens disorders such as cataracts.

By Sanjay Mishra
July 27, 2015

Anticancer olive compounds

Compounds found in olives and olive oil have anticancer activity, which may contribute to the cancer preventive properties attributed to the Mediterranean diet.
By Leigh MacMillan
July 24, 2015

How to trick a wily virus

Vanderbilt investigators have discovered how human antibodies induced during testing of an experimental “bird flu” vaccine kill the virus.
By Sanjay Mishra
July 23, 2015

Targeting bone metastasis

The rigidity of the bone extracellular matrix increases the ability of tumor cells to destroy bone, suggesting new targets for anticancer drug development.
By VUMC News and Communications
July 15, 2015

Drug signaling networks

Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action.
By Leigh MacMillan
July 13, 2015

Hhex on cancer

A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production.
By Henry H. Ong
July 10, 2015

Delivering cells for heart repair

A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair.
By Leigh MacMillan
July 9, 2015

Signals of schizophrenia

Vanderbilt researchers have discovered a possible molecular mechanism of schizophrenia that could lead to new treatments for the disorder.
By VUMC News and Communications