Aliquots - Research Briefs

June 26, 2013

Insights on glaucoma gene mutations

Glaucoma-causing mutations in the gene for myocilin reduce secretion of the protein into the aqueous humor, suggesting a new option for treatment.

By Leigh MacMillan
June 24, 2013

Predicting cancer’s response to therapy

Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding.

By Leigh MacMillan
Heart illustration thumbnail
June 21, 2013

Rhythm response tied to gene variant

A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder.

By Leigh MacMillan
June 20, 2013

Disease linked to cell traffic jams

Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.

By Leigh MacMillan
June 12, 2013

Antacids: risky for premature babies

Antacids that block a certain enzyme pose a risk for a common cardiac problem in premature infants.

By Leigh MacMillan
June 10, 2013

Factor’s yin-yang tumor effects

A factor produced by most malignant cells can both promote and inhibit tumor growth – an insight that is critical to using cancer drugs developed to block this factor.

By Leigh MacMillan
June 7, 2013

Autism speeds motion perception

Children with autism spectrum disorder are better at perceiving the motion of certain objects than are typically developing children their age.
By Bill Snyder
June 6, 2013

Matrix member key to insulin resistance

A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.
By Leigh MacMillan
May 15, 2013

Inner ear’s role in bone remodeling

The inner ear system that senses gravity and movement plays a role in bone remodeling – a finding that has clinical implications for space travel and for patients with inner ear disorders.
By Leigh MacMillan
May 13, 2013

Salt revs stomach bug’s cancer impact

A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population.
By Leigh MacMillan
May 10, 2013

Profiling heart cells

A “profile” of the genes and regulatory networks that govern early heart valve development lay the groundwork for generating valves from a patient’s own cells.
By Leigh MacMillan
May 9, 2013

Dual-action enzyme protects esophagus

An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus.
By Leigh MacMillan
May 1, 2013

Taking the ‘noise’ out of protein data

Vanderbilt researchers have developed a novel algorithm to improve results from proteomic studies.
By Leigh MacMillan
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