John H. Exton, MBChB, MD, PhD, professor of Molecular Physiology and Biophysics, emeritus at Vanderbilt University, whose research provided fundamental insights into how many biologically active compounds control cellular physiology, died Dec. 18. He was 89.

Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury.

An international team of investigators has found that mild to moderate reduction in kidney function may cause cardiovascular disease, even in people without symptoms of heart disease or diabetes.

A Vanderbilt study found that higher levels of excess oxygen given to patients under general anesthesia add risk of injury to the kidneys, lungs and heart.

An imaging-based risk score can identify patients with Duchenne muscular dystrophy who are at greater risk of early mortality, allowing more intensive treatment and potentially prolonging life.

Natural language processing of notes in electronic health records can identify suicidal behavior and could be used to directly improve real-time risk prediction algorithms.