American Journal of Human Genetics Archive — Page 1 of 2
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October 1, 2020
Genes spell penicillin allergy risk
Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. -
June 12, 2020
Robotic technology speeds arrhythmia gene classification
Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions. -
August 26, 2019
Cancer susceptibility genes
Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations. -
April 24, 2019
Study merges big data and zebrafish biology to reveal mechanisms of human disease
In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease. -
May 4, 2018
New breast cancer targets
A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer. -
January 12, 2017
Investigators apply game theory to study of genomic privacy
It comes down to privacy — biomedical research can’t proceed without human genomic data sharing, and genomic data sharing can’t proceed without some reasonable level of assurance that de-identified data from patients and other research participants will stay de-identified after they’re released for research. -
March 17, 2016
Study explores gene’s role in protecting HIV patients from TB
An international research team led by scientists from Vanderbilt University Medical Center has identified a genetic variant that protects people with HIV from developing active tuberculosis. The variant is near the gene encoding the infection-fighting cytokine IL-12.