cancer

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photo of William Dupont
June 5, 2023

Study discovers that tumor mutation burden predicts survival outcome

The expected course of a patient’s cancer prognosis has traditionally been judged by its type, stage and microscopic aggressiveness, but patients with the same presentation can still have widely divergent outcomes. Researchers from Vanderbilt-Ingram Cancer Center have discovered that differences in tumor mutation burden are a major reason for this divergence.

By Tom Wilemon
May 31, 2023

Liquid biopsy test may detect early-stage and low DNA-shedding cancers

Vanderbilt research shows that a liquid biopsy-based multicancer early detection (MCED) test could detect 12 types of cancers, including low DNA-shedding cancers and early-stage cancers.

By Tom Wilemon
May 11, 2023

Study shows palliative care provided at point of oncology surgery does not improve patient outcomes

New Vanderbilt research provides evidence that the addition of palliative care services earlier in the disease process, specifically to patients having surgery for cancer, does not demonstrate benefits to the patients.

By Jill Clendening
May 4, 2023

Better adenoma detection

Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans.

By Sarah E. Glass
March 23, 2023

Decoding cell division machinery

Phosphate modification regulates the cell localization of Cdc15, one of the main controllers of cell division, to fine tune the assembly of cell division machinery.

By Caroline Cencer 
February 16, 2023

Breast cancer genetics: new insights

Largest genetic study of breast cancer to date identifies 222 genetic risk loci, 137 genes and multiple signaling pathways associated with risk, providing important new insights.

By Leigh MacMillan
February 16, 2023

Targeted therapy for neuroendocrine tumors

Cancer therapies that target VEGF receptor appear safe and effective for patients with pancreatic and non-pancreatic neuroendocrine tumors, meta-analysis of phase 2/3 clinical trials demonstrates.
By Kelsey Pinckard
January 26, 2023

Nobel laureate Nurse set for year’s first Discovery Lecture

Nobel Prize-winning geneticist and cell biologist Sir Paul Nurse, PhD, will be at Vanderbilt Thursday, Feb. 9, to deliver the year's first Discovery Lecture.
By Bill Snyder
November 17, 2022

Surgery for hereditary breast cancer

Similar rates of bilateral mastectomy in women with inherited mutations in high- and moderate-penetrance genes raises concerns about possible overtreatment of some patients, Vanderbilt researchers report.
By Leigh MacMillan
November 15, 2022

As a medical student, Joseph Fusco was diagnosed with cancer. That experience influences the way he treats his young patients every day.

He gave up baseball to become a surgeon. That decision may have saved his life.
By Jessica Pasley
September 29, 2022

Policy, resources crucial for lung cancer screening: study

Vanderbilt reseach shows that resources for lung cancer screening programs increased the number of veterans screened.
By Leigh MacMillan
September 22, 2022

Nerve cells and cancer progression

Immature nerves and neural precursor cells increase in density as a type of premalignant tumor in the pancreas progresses to invasive disease, suggesting that blocking these cells may arrest malignant progression.
By Leigh MacMillan
September 13, 2022

Cancer registries and sarcoma research

The number of sarcoma research studies that use the two largest U.S. cancer registries is increasing, but over one-third of studies that asked the same research question reported conflicting findings.
By Leigh MacMillan
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