An image of cancer treatment response

An MRI method developed by Vanderbilt researchers uses imaging data to derive cell size and could be added to clinical practice for better monitoring of breast cancer treatment response.

Improved imaging for kidney disease

Vanderbilt researchers identified optimal MRI parameters for estimating the severity of polycystic kidney disease, a common inherited disorder that can lead to end-stage renal failure.

Better adenoma detection

Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans.

Improving lung nodule diagnosis

Adding blood and imaging biomarkers to a clinical prediction model could improve diagnostic accuracy for the 1.6 million lung nodules detected each year, many through expanded lung cancer screening programs.

Nutrient absorption disease model

Vanderbilt researchers developed a model of a patient-specific mutation to explore the pathology of microvillus inclusion disease, a genetic disorder that causes life-threatening diarrhea.

Highly multiplexed, untargeted MALDI imaging mass spectrometry data reveal the localization of various lipids and metabolites to specific functional regions of the nephron, the kidney's filtering unit (right).

Grants spur efforts to create molecular ‘atlases’ of organs

Vanderbilt researchers have received three grants totaling $13.6 million from the National Institutes of Health to develop molecular “atlases” of the brain, kidney, eye and other tissues.

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