inflammation

February 12, 2014

Obesity sends immune cells to the brain

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.

By Leigh MacMillan
December 12, 2013

Therapeutic target for gastric cancer

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.

By Leigh MacMillan
October 11, 2013

New target for stopping inflammation

Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.

By Bill Snyder
August 9, 2013

‘Yo-yo dieting’ inflames fat tissue

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

By Leigh MacMillan
August 8, 2013

Nuclear shield against cell death

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

By Bill Snyder
November 6, 2012

Bacterial signals in sarcoidosis

Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death.

By VUMC News and Communications