inflammation Archive — Page 4 of 6

November 29, 2018

Parsing diabetic skin infections

Vanderbilt researchers have discovered a role for an inflammatory mediator in diabetic skin infections, suggesting new therapeutic targets for this common complication of diabetes.

Two smiling researchers stand in a laboratory surrounded by shelves of equipment and supplies.
November 1, 2018

Team’s findings show glutamine metabolism affects T cell signaling

The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.

Five stylized human figures in orange, yellow, red, green, and blue standing side by side; the yellow and green figures are depicted with skirts.
October 12, 2018

Asthma’s androgen connection

New findings may explain why the prevalence of asthma is higher in women and suggest that testosterone derivatives may be useful for treating more severe types of asthma.

July 2, 2018

SMAD4 clue to colon cancer

Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.

3d rendering white blood cells with red blood cells
May 9, 2018

Putting the brakes on sepsis

An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection.

Whole turmeric roots beside a mound of bright yellow-orange turmeric powder on a white background.
January 16, 2018

A spicy finding

Vanderbilt researchers have discovered that curcumin — the active ingredient in the spice turmeric — needs to be metabolically activated to exert anti-inflammatory effects.