NCI

New findings about proteins involved in DNA repair are important for understanding why some cancers are more or less resistant to certain therapies.

An international team of researchers has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.

A protein involved in binding cells together helps maintain the integrity of the intestinal mucosa and plays a protective role in ulcerative colitis.

New findings open opportunities to understand mechanisms of DNA repair for a toxic form of DNA damage.

Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.

Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis.

A five-year National Cancer Institute grant will fund an interdisciplinary research center for the study of small cell lung cancer, a highly aggressive, incurable form of the disease.