NIDDK

July 19, 2018

Novel insights on “leaky” gut

A protein involved in binding cells together helps maintain the integrity of the intestinal mucosa and plays a protective role in ulcerative colitis.

By Niyati Vachharajani
July 2, 2018

SMAD4 clue to colon cancer

Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.

By Bill Snyder
July 2, 2018

Mother knows best

The first demonstration of bacterial DNA in mammalian fetal intestinal tissue suggests that the mother’s microbiome moves into the fetal intestine.

By Leigh MacMillan
April 23, 2018

Toxin floats on lipid rafts

The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells.

By Leigh MacMillan
April 20, 2018

Disease-fighting antibody production

New research links nutrient-responsive cellular signaling to the antibody-mediated immune response.

By Leigh MacMillan
March 23, 2018

Voluntary exercise and energy balance

Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered.

By Leigh MacMillan
March 22, 2018

Kidney disease imaging

Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury.
By Leigh MacMillan
March 15, 2018

Peek named to serve on NIDDK Advisory Council

Richard Peek, MD, director of the Vanderbilt Digestive Disease Research Center (VDDRC) and chief of the Division of Gastroenterology, Hepatology and Nutrition, has been appointed to serve on the advisory council of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
By Jill Clendening
February 14, 2018

A new target for neuroblastoma

Vanderbilt investigators have discovered that a sirtuin protein has oncogenic properties in neuroblastoma cells — and that blocking it reduces their growth and tumor-like characteristics.
By Leigh MacMillan
February 13, 2018

Cognition in rare hormonal disorder

Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder.
By Leigh MacMillan
January 31, 2018

Cell skeleton and the brush border

Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines.
By Leigh MacMillan
January 11, 2018

Lighting up iron levels

A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease.
By Leigh MacMillan
December 19, 2017

Forming memories through CaMKII

Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory.
By Sanjay Mishra
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