NIH

September 13, 2018

Healthy antibodies reverse diabetes

Vanderbilt researchers have discovered that IgM-type antibodies appear to play a protective role to prevent the development of type 1 diabetes — and that purified IgM antibodies can reverse the disease.

By Leigh MacMillan
array of test tubes with pipette dropping fluid into one
September 5, 2018

Unleashing TIGER on small RNAs

Vanderbilt investigators have developed a new analytical tool to identify, quantify and analyze small RNAs.

By Leigh MacMillan
August 30, 2018

A brain-builder called “Shh”

New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

By VUMC News and Communications
August 30, 2018

Energetic gene switch

New findings link flux through glycolysis, which produces cellular energy, with transcription and gene expression via histone modification.

By Bill Snyder
August 30, 2018

Investigators find that bile acids reduce cocaine reward

Bile acids — gut compounds that aid in the digestion of dietary fats — reduce the desire for cocaine, according to a new study by researchers at Vanderbilt and the University of Alabama at Birmingham.

By Leigh MacMillan
August 16, 2018

Risk factors for faulty rhythms

Risk factors for arrhythmias after heart surgery in infants include medications, infant age and higher surgical complexity, but not two genetic variants examined by Vanderbilt researchers.

By Leigh MacMillan
August 16, 2018

A new target for lung cancer

Vanderbilt researchers have identified a new vulnerability in lung cancer — the transporter protein xCT — that may a therapeutic target for the disease.
By Leigh MacMillan
August 16, 2018

YAP after acute kidney injury

Activation of the signaling protein YAP may be a target for treating acute kidney injury, which affects up to 20 percent of hospitalized patients.
By Sanjay Mishra
August 16, 2018

Predictive models for gene regulation

Using new computational approaches to understand the behavior of cells should aid efforts to predict how mutations affect cell function and how diseases respond to drug combinations.
By Bill Snyder
August 2, 2018

Repairs in the basement membrane

Studies in fruit flies have shed light on how the basement membrane — a sheet-like scaffold that wraps around most animal tissues — is repaired after being damaged.
By Sanjay Mishra
August 2, 2018

Genetic balancing act

New findings about proteins involved in DNA repair are important for understanding why some cancers are more or less resistant to certain therapies.
By Meredith Jackson
August 2, 2018

How asters form

New findings shed light on the formation of microtubule structures that support cellular processes ranging from cell division to intracellular transport.
By VUMC News and Communications
August 2, 2018

Connecting an asthma gene to leukemia

A receptor previously implicated in asthma may also play roles in other allergic diseases and in leukemia, Vanderbilt researchers have discovered.
By Leigh MacMillan
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