NIH Archive — Page 6 of 93

Top-view arrangement of potassium-rich foods on a blue wooden surface, including bananas, avocado, potatoes, mushrooms, tomatoes, broccoli, grapefruit, kiwi, carrots, nuts, beans, and a bowl of dried fruit.
January 19, 2023

Low potassium injures kidney

Vanderbilt researchers have discovered that low dietary potassium causes direct kidney injury, suggesting potential new targets for treating chronic kidney disease.

Jeffrey Rathmell, PhD, left, and Kelsey Voss, PhD, led a multidisciplinary team that identified iron metabolism in T cells as a potential target for treating lupus.
January 13, 2023

Study identifies potential new approach for treating lupus

A Vanderbilt study found that targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus — the most common form of the chronic autoimmune disease lupus.

Young woman in a plaid shirt covers her mouth with one hand while clutching her abdomen with the other, appearing nauseated or unwell.
January 10, 2023

Anti-nausea drug response in children

Genetic variation in a metabolic enzyme was not associated with response to the anti-nausea drug odansetron in children, Vanderbilt researchers report.

Medical illustration of a human torso showing the trachea, branching airways, and both lungs, with several clustered blue nodules depicted inside the lungs.
January 9, 2023

Novel lung cancer biomarker

Autoantibodies against the p53 tumor suppressor protein may be a novel biomarker for identifying people, especially African Americans, at high risk for lung cancer.

Stylized side-profile illustration of a human head with the skull rendered translucent to reveal a network resembling brain blood vessels, dissolving into particles against a peach background.
January 6, 2023

Early effects of Huntington disease

Impairments in brain executive function happen earlier than motor symptoms in people with the gene mutation that causes Huntington disease, suggesting younger ages and cognitive symptoms be considered for any future clinical trials.

Abstract illustration of colorful DNA double-helix strands forming a sweeping arc across a purple background with bright radiating light.
January 6, 2023

MicroRNAs linked to lipid damage

VUMC researchers have linked microRNAs with systemic lipid peroxidation, a discovery that could point to new therapeutic targets for a variety of diseases.