NIH Archive — Page 4 of 93

White, black, and pink pills arranged to form a pair of lungs on a light blue background.
April 24, 2023

Novel drugs have potential for treating tuberculosis

Drug-resistant tuberculosis is on the rise, and novel antibacterial drugs called SPTs have potential for treating the deadly lung infection.

Person sitting cross-legged on a bed and holding their lower abdomen, with a red glow highlighting the abdominal area.
April 20, 2023

Overactive bladder and anxiety

Anxiety and psychological stress impact hypersensitivity mechanisms in women that could contribute to overactive bladder — a frequent and sudden urge to urinate that is difficult to control.

Silhouette of a person facing a glowing DNA double helix, overlaid with floating binary digits in a blue-toned digital composition.
April 20, 2023

Genetics and chronic pain

Polygenic risk scores — scores that reflect the influence of common genetic variants — could be used to predict the likelihood of developing chronic overlapping pain conditions and guide biomarker and targeted prevention efforts.

From left, Xiang Ye, PhD, Suba Rajendren, PhD, Antiana Richardson, and John Karijolich, PhD, are studying how the cancer-causing virus KSHV commandeers host gene expression and regulatory machinery.
April 20, 2023

Study details RNA editing in virus-infected cancer cells

Vanderbilt researchers detail the landscape of RNA editing — a form of RNA modification — in primary effusion lymphoma cells during Kaposi’s sarcoma-associated herpesvirus infection and identify an edited viral microRNA that is critical for infection.

Green sugar cane field with vehicle tracks in the foreground and a cluster of high-rise buildings on the horizon beneath a cloudy sky.
April 11, 2023

COVID on Twitter: town vs. country

A natural language processing analysis of 407 million tweets from May 2020 to January 2022 captures the rural-urban divide regarding COVID-19.

Illustration of an electronic health record on a tablet, showing a medical cross inside a color-coded chart, with icons for blood, microscopy, heart monitoring, test tubes, and DNA analysis connected around it.
April 10, 2023

The problem with the problem list

Algorithms to infer missing problems and suggest that they be added to electronic health records improved problem list completeness, with benefits for clinical care, patient comprehension of health conditions and population health.