Proceedings of the National Academy of Sciences Archive — Page 1 of 4

Stylized glowing human brain surrounded by bright white-blue electrical lightning against a dark blue background.
October 16, 2023

VUMC scientists record powerful signal in the brain’s white matter

Vanderbilt researchers report that when people who are having their brains scanned by fMRI perform a task, like wiggling their fingers, certain signals increase in white matter throughout the brain, which has long been thought to play a lesser role the more the brain’s more energetic gray matter.

Frank Mason, PhD, left, Kimryn Rathmell, MD, PhD, and their colleagues have identified an early event in the development of cancer, one that could lead to new ways to prevent it. (photo by Erin O. Smith)
September 20, 2023

VUMC study reveals critical first steps to cancer

A new study by Vanderbilt researchers provides a remarkably detailed view of the earliest events leading to the development of cancer, and of potential new ways to prevent it.

Houra Merrikh and Juan Carvajal-Garcia, PhD, are studying how to prevent cancer therapy resistance. (photo by Erin O. Smith)
September 1, 2023

Foundation funds research to block drug resistance in cancer treatment

The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation has funded an ambitious initiative to overcome one of the most perplexing and frustrating mysteries of cancer treatment — how to prevent drug resistance.

Multi-panel medical imaging comparison showing whole-body views at left and paired coronal chest and neck scans in fused, grayscale CT, and color-coded formats; red arrows and a dashed red line mark areas in the lower set.
January 12, 2023

Study may lead to new diabetes, heart disease treatments

Vanderbilt research found that deletion of an autophagy-participating factor named PIK3C3 from the fat cells of mice led to compromised body temperature control, abnormal blood lipid levels, fatty liver and diabetes.

Silas LaCagnin gazes at his mother, Ansley LaCagnin, while she sings to him.
November 3, 2022

Study finds sensitivity to musical rhythm supports social development in infants

A new study shows engaging infants with a song provides a ready-made means for supporting social development and interaction.

Medical illustration of two lungs on a black background, with a red highlighted mass in the upper region of the right lung.
July 28, 2022

Study reveals need for matching targeted therapies with EGFR subtypes

A Vanderbilt study suggests that clinicians should take a deeper dive into distinguishing EGFR mutations when prescribing targeted therapies for non-small-cell lung cancers.