Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.

A $10 million endowed gift will fund translational research, support clinical programs and create an endowed chair within the Department of Psychiatry.

According to a new study by Vanderbilt researchers, normal brain aging patterns in patients with a psychotic disorder occur at an accelerated rate, impacting the patient’s cognitive functioning and suggesting treatment intervention in the early psychosis period may improve long-term outcomes.

Two Vanderbilt University researchers have been awarded Blake A. Jenkins Discovery Awards in support of basic and/or translational research into bipolar disorder and related conditions with an emphasis on early detection, intervention and utilizing brain imaging.

Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting.

Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions.

When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects.