Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases.

A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing.

Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer.

Vanderbilt University researchers have created a zebrafish model of skeletal muscle insulin resistance that could help improve diabetes treatment.

A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies.

Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.

A zebrafish model of a severe mitochondrial disease will be useful for developing new therapeutic approaches.