An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.

Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways.

Vanderbilt-Ingram Cancer Center (VICC) has joined an international consortium of leading cancer centers to share genomic data from patients in an effort to accelerate the pace of cancer research and improve precision medicine.

Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

Nearly 39,000 new cancers associated with the human papillomavirus (HPV) will be diagnosed in the United States this year. Although HPV vaccines can prevent the majority of these cancers, vaccination rates remain low across the country.

Tumors cause the intracellular material surrounding them to stiffen. Softening this protective layer could make existing cancer treatments more effective, according to new research.

Researchers in the Schools of Medicine and Engineering at Vanderbilt University have discovered a proteomic “signature” from the airways of heavy smokers that could lead to better risk assessment and perhaps new ways to stop lung cancer before it starts.