Vanderbilt researchers used novel MRI methods to noninvasively quantify measures of neurofluid circulation and found that hypertrophy of a site of cerebrospinal fluid egress may be related to amyloid-beta retention in Alzheimer’s disease.

Vanderbilt researchers identified optimal MRI parameters for estimating the severity of polycystic kidney disease, a common inherited disorder that can lead to end-stage renal failure.

Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans.

Adding blood and imaging biomarkers to a clinical prediction model could improve diagnostic accuracy for the 1.6 million lung nodules detected each year, many through expanded lung cancer screening programs.

A collaborative team at Vanderbilt is transforming the diagnosis and treatment of lipedema, a debilitating, abnormal deposition of fatty tissue that afflicts an estimated 17 million women in the United States.

Vanderbilt researchers developed a model of a patient-specific mutation to explore the pathology of microvillus inclusion disease, a genetic disorder that causes life-threatening diarrhea.

New findings from Vanderbilt neurologists suggest that cardiovascular disease may increase the spaces surrounding blood vessels in the brain and lead to cognitive decline.