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clinical trial Archives

End-stage kidney disease study seeks to delay dialysis

Aug. 31, 2017—Vanderbilt University Medical Center (VUMC) is studying the safety of a possible treatment for diabetic kidney disease that would delay or prevent the need for kidney replacement such as dialysis.

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Block estrogen to treat lung disease

Aug. 17, 2017—Based on findings from Vanderbilt investigators and others, clinical trials of estrogen inhibition for pulmonary arterial hypertension have recently been approved and funded by the National Institutes of Health.

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Vanderbilt begins Phase 1 trials of new Alzheimer’s drug

Aug. 7, 2017—Developed at Vanderbilt, VU319 is designed to precisely target a specific neuron receptor associated with cognitive function while avoiding potentially dangerous side effects.

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Clinical trial to test Singulair to treat bladder pain syndrome

Jul. 20, 2017—Vanderbilt University Medical Center is currently enrolling women to participate in a study looking at the drug Montelukast to treat interstitial cystitis/bladder pain syndrome (IC/BPS).

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Study uses child’s own immune system against type one diabetes

Jun. 22, 2017—Eighteen-year-old Grace Long had just been accepted at the renowned United States Naval Academy, with plans to become a nuclear engineering officer. Then, she learned she had type 1 diabetes, an immediate disqualifier for military service.

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Horn to lead lung cancer combination therapy trial

Mar. 30, 2017—Leora Horn, M.D., M.Sc., associate professor of Medicine and clinical director of the Thoracic Oncology Program at Vanderbilt-Ingram Cancer Center (VICC), has been selected to lead a clinical research trial of combination therapy using two targeted drugs for the treatment of a specific form of lung cancer.

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VUMC testing device to reduce stroke risk in arrhythmia patients

Feb. 9, 2017—Vanderbilt University Medical Center (VUMC) is the first in the state to enroll patients in a clinical trial testing the effectiveness of the newest implantable device used to reduce stroke risk in patients with non-valvular atrial fibrillation (AF), the most common form of arrhythmia.

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Trial to test aortic valve technique in lower-risk patients

Oct. 27, 2016—In 2011, doctors at the Vanderbilt Heart and Vascular Institute performed the state’s first transcatheter valve-replacement (TAVR) procedure for high-risk patients suffering from aortic stenosis, the most common valvular heart disease in the United States.

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VICC trial putting lung cancer therapy to the test

Oct. 20, 2016—Vanderbilt-Ingram Cancer Center (VICC) is leading a Phase 3 global trial of a cancer therapy that was initially tested and validated in a VICC research laboratory. One of the first patients treated with the therapy came to VICC after a bump on the head led to an unexpected cancer diagnosis.

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First subject enrolled in international HIV prevention study

Apr. 14, 2016—This month an international HIV prevention trial was launched that is testing the infection-preventing prowess of a monoclonal antibody called VRCO1.

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VUMC study finds statins do not ease kidney injury following cardiac surgery

Feb. 23, 2016—Among doctors, it is widely believed that a class of drugs called statins, which are used to lower cholesterol, might help patients tolerate the stress of cardiac surgery. Not so, according to a five-year, placebo-controlled, double-blinded randomized clinical trial conducted at Vanderbilt University Medical Center, published today in the Journal of the American Medical Association....

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Diabetes trial targets body’s ability to produce insulin

Sep. 10, 2015—Kiersten Eaddy had long looked forward to her high school graduation day and joining her classmates to celebrate the accomplishment.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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