Department of Cell and Developmental Biology

colored representation of cells and glia

Discovery sheds light on protein key to nerve cells’ myelin sheath

Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.

NOTCH1 role in heart development

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

Polarity protein role in cell survival

Vanderbilt investigators have identified an unexpected link between cell survival and the polarized delivery of proteins to the surface of mammary epithelial cells.

A molecular clue to longevity

In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.

Molecular motors expert Spudich set for next Discovery Lecture

James Spudich, Ph.D., renowned for his studies of proteins that function as molecular motors, will deliver the next Flexner Discovery Lecture on Thursday, April 6.

Memorial service for Professor Vivien Casagrande set for April 12

A memorial service for Professor Vivien Casagrande is planned for April 12 in Benton Chapel.

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