Department of Pathology Microbiology and Immunology

Vanderbilt University Medical Center investigators have identified a key molecular player in the early events of the inflammatory response to infection. The findings suggest new therapeutic possibilities for enhancing the inflammatory response to protect against pathogens and for blocking inflammation gone awry in diseases like arthritis and atherosclerosis.

After an extensive national search Alice Coogan, MD, interim chair of the Department and professor of Pathology, Microbiology and Immunology (PM&I), has been named as the department’s next chair, effective immediately. Coogan will be the seventh chair of the department and the first female chair.

False positives on urine drug screens are common and are frequently due to cross-reactivity of these tests to medications. Last year, Vanderbilt University Medical Center researchers Jacob Hughey, PhD, assistant professor of Biomedical Informatics, and Jennifer Colby, PhD, at that time assistant professor of Pathology, Microbiology and Immunology, devised, tested and published a method to systematically identify medications that interfere with screenings for drugs of abuse.

Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has received a V Scholar Award to support her studies of the links between obesity, the gut microbiome and colorectal cancer.

Peptides derived from the antimicrobial peptides secreted by frogs could function as microbicides to limit HIV transmission, while sparing protective vaginal bacteria.

An innovative Vanderbilt program that brings together scientists and artists with the shared goal of scientific communication is set to expand with support from a three-year grant from the Burroughs Wellcome Fund.

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found.