Division of Allergy Pulmonary and Critical Care Medicine

The 2022 Vanderbilt Translational Research Forum exemplified the range of studies conducted at Vanderbilt University Medical Center that are translating scientific discovery into clinical practice.

A Vanderbilt study looked at the oxygen saturation target that results in optimal outcomes — number of days alive and free of mechanical ventilation — in 2,500 critically ill adults receiving mechanical ventilation.

Blocking thromboxane-prostanoid receptor signaling protected animals from lung fibrosis in preclinical models, suggesting a new treatment for IPF — a chronic, progressive lung disorder that often kills within 3-5 years of diagnosis.

Black patients in the ICU were more likely to have low or high blood oxygen levels than white patients, even when a pulse oximeter indicated 92-96% oxygen saturation, Vanderbilt researchers found.

Efforts to correct mistaken or outdated penicillin allergy records are destined to spread to more patient care areas at Vanderbilt University Medical Center.

ICU survivors who have impaired exercise capacity months after discharge may have damaged muscle mitochondria — the energy powerhouses of the cell, Vanderbilt researchers propose.

Using a high-throughput informatics technique and electronic health records, Vanderbilt researchers found that COVID-19 survivors had an increased risk for more than 40 new diagnoses.