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eMERGE Archives

Probing statin-associated diseases with genetics

Jul. 12, 2021—Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

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Roden honored with Oscar B. Hunter Career Award in Therapeutics

Mar. 15, 2021—Dan Roden, MD, Senior Vice President for Personalized Medicine at Vanderbilt University Medical Center, received the Oscar B. Hunter Career Award in Therapeutics last week at the virtual annual meeting of the American Society for Clinical Pharmacology and Therapeutics.

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VUMC-led network to focus on polygenic risk for common diseases

Jul. 1, 2020—With the aid of a $75 million, five-year grant renewal, the Electronic Medical Records and Genomics Network (eMERGE) will venture beyond its current focus on monogenic disease to scoring research participants’ relative risk for complex heritable diseases such as cardiovascular disease, chronic kidney disease and type 2 diabetes.

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Getting the goods on obesity

Nov. 19, 2019—Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit.

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Grants spur effort to add genetic data to EMR

Sep. 10, 2015—Vanderbilt University researchers have received two major federal grants — totaling $7.6 million over four years — to support groundbreaking research aimed at making genetic information a routine part of patients’ electronic medical records.

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First-ever study uses EMRs to spot new disease associations

Dec. 5, 2013—Vanderbilt University Medical Center researchers and co-authors from four other U.S. institutions from the Electronic Medical Records and Genomics (eMERGE) Network are repurposing genetic data and electronic medical records to perform the first large-scale phenome-wide association study (PheWAS), released today in Nature Biotechnology.

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Study applies random genotype sets to new disease

Jan. 5, 2012—A new study in the American Journal of Human Genetics, led by Vanderbilt researchers Josh Denny, M.D., M.S., and Dana Crawford, Ph.D., takes random volumes of human genotypes and matches them with data siphoned from de-identified medical records and sheds new light on the genetic basis of the common disease hypothyroidism. In a research lab,...

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