A recent study shows what's involved in bringing polygenic risk to bear in chronic disease clinical decision-making.

There are many more known pathogenic gene variants than there are clinical solutions for dealing with them. A new Vanderbilt Health-led NIH-funded research consortium will use machine learning and AI to help usher in genome-informed clinical decision support.

Ten Ukrainian health care professionals visited the Vanderbilt Transplant Center, Vanderbilt-Ingram Cancer Center and the Department of Biomedical Informatics.

“For too long, patients who survive these reactions have been left without clear answers about why it happened, which medicines are safe, and what the future holds,” said Elizabeth Phillips, MD, who is leading the consortium.

The scientific statement suggests improving women’s kidney care by recognizing how women’s unique biology and social factors affect kidney health and designing research that includes sex-specific analyses of kidney function and chronic kidney disease medications.

Individuals taking the drug saw a significant drop in inflammatory cell clumps within just two weeks, and the reduction grew even stronger by week 12.

Since its launch in 2024, the program has expanded to serve clinicians across West, Middle and East Tennessee through regional partnerships with the University of Memphis and the University of Tennessee at Chattanooga.