Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.

Patients treated in intensive care units across the globe enter their medical care with no evidence of cognitive impairment but often leave with deficits similar to those seen in patients with traumatic brain injury (TBI) or mild Alzheimer’s disease (AD) that persist for at least a year, according to a Vanderbilt University Medical Center study published today in the New England Journal of Medicine.

Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease.

A coronavirus protein is required for replication of the viral genome and may be a good treatment target for SARS and other diseases caused by coronaviruses.

Children who receive a vaccine to prevent blood and ear infections may be reducing the spread of pneumonia to the rest of the population, especially their grandparents and other older adults.

Children with autism spectrum disorder are better at perceiving the motion of certain objects than are typically developing children their age.

Clinical pharmacologist Jens Titze, M.D., and his colleagues have identified a new cast of cells and molecules that function in the skin to control sodium balance and blood pressure.