COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.

The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers reported May 2 in Nature Methods.

The true incidence of hazing in youth sports is unknown because victims don’t report the mistreatment or fail to recognize it as hazing, according to a review of scientific literature on the subject by a team of Vanderbilt University Medical Center researchers.

Anesthesiology resident Loren Smith, M.D., Ph.D., recently received two national research awards: the Margaret Wood Resident Research Award, from the Association of University Anesthesiologists (AUA); and the 2016 Young Investigator Award, from the Society of Critical Care Anesthesiologists (SOCCA).

Vanderbilt researchers have discovered that activation of a certain signaling pathway protects brain cancers from targeted therapies, suggesting that using therapeutics that block both pathways may be a promising treatment.

A newly discovered mechanism that helps cancer cells avoid destruction by immune system cells may improve immunotherapies.

A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.”