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drug repurposing Archives

VUMC and Roivant Social Ventures announce collaboration to develop therapies for underserved populations

Jul. 6, 2022—Vanderbilt University Medical Center and Roivant Social Ventures (RSV) this week announced an intention to collaborate in developing therapies for traditionally underserved populations and diseases.

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New method enhances efforts to identify drug repurposing targets

Jan. 20, 2022—Researchers at Vanderbilt University Medical Center have developed a new method for identifying drugs for the repurposing trials that can lead to new indications for drugs already in use.

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VUMC tests drugs for COVID outpatient treatment

Nov. 11, 2021—  by Paul Govern Vanderbilt University Medical Center has joined a nationwide study to evaluate repurposed medications in the search for effective, safe treatments for mild-to-moderate COVID-19. Repurposed medications are those already approved by the U.S. Food and Drug Administration for other indications. ACTIV-6, “The Randomized Trial to Evaluate Efficacy of Repurposed Medications,” is a...

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Certain drug exposures correlate with reduced COVID severity: study

Aug. 12, 2021—Analyzing electronic health records (EHR) of 9,748 patients diagnosed with COVID-19, Cosmin Bejan, PhD, Elizabeth Phillips, MD, and colleagues at Vanderbilt University Medical Center asked whether COVID disease severity correlated with any drugs that happened to be taken by these patients in the months leading up to their diagnosis.

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VUMC aids national effort to repurpose drugs for COVID-19

Apr. 19, 2021—Vanderbilt University Medical Center (VUMC) has been named Data Coordinating Center (DCC) for a nationwide platform of studies aimed at “repurposing” existing drugs to treat mild to moderate symptoms of COVID-19.

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VUMC’s program to repurpose drugs lands international acclaim

Jul. 23, 2020—Vanderbilt University Medical Center is attracting international attention for its proposal to repurpose existing drugs for new uses in ways that can dramatically improve access to medicines by billions of people throughout the world.

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Vanderbilt University Medical Center among top 100 proposals for MacArthur Foundation $100 million grant

Feb. 19, 2020—The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Change competition for a single $100 million grant to help solve one of the world’s most critical societal challenges.

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Treating C. diff: new purpose for an old drug?

Sep. 24, 2019—An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.

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Clinical study tests drug that may prevent cancer metastasis

Jul. 8, 2019—A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center.

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VUMC drug repurposing initiative gaining momentum

Apr. 19, 2018—Drug repurposing involves establishing an additional approved indication for a drug already at market.

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Grant bolsters study of potential new therapy for C. diff infection

Mar. 22, 2018—According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis.

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Study explores anti-viral potential of existing drugs

Sep. 15, 2016—Emerging viral infections like Zika keep popping up around the world in such quick succession that medicine is having a hard time keeping up. It can take 15 years and more than a billion dollars to bring a new drug to market.

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Recent Stories from VUMC News and Communications Publications

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