Proceedings of the National Academy of Sciences (PNAS) (journal) Archive
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May 5, 2020
A dual-purpose metabolic switch
John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules. -
January 29, 2020
Protein research seeks to induce tumor regression
Understanding how MYC interacts with WDR5 and other cofactors could lead to the development of new drugs that can effectively block MYC and stop many cancers in their tracks. -
October 31, 2019
Imaging host-pathogen battle for metal
An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies. -
October 17, 2019
Less inflammation = better healing
Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes. -
October 3, 2019
A step toward gastric cancer
New research findings provide insight into the detrimental events that develop in response to H. pylori infection. -
April 25, 2019
Low oxygen and antibody responses
Mark Boothby and colleagues are exploring the factors that contribute to antibody production and quality, which are key to our defense against pathogens and response to vaccines. -
March 28, 2019
Cancer prevention drug also disables H. pylori bacterium
A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.