Research

Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies.

A Vanderbilt lung cancer patient’s exceptional response to different types of therapies spurred research that suggests lung cancer patients with specific gene alterations may benefit from combination therapy that targets two different cancer pathways.

Vanderbilt-led research found regular blood transfusion therapy significantly reduces the recurrence of strokes in children with sickle cell anemia who have previously had "silent" strokes.

Reporting last week in the journal Cell, researchers from Oregon Health and Science University, Harvard Medical School and Vanderbilt University describe the first “four-dimensional” picture of a brain receptor that plays a key role in learning and memory.

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

Researchers at Vanderbilt University, the University of Arizona and Phoenix Children’s Hospital have discovered what triggers a rare but devastating diarrheal disease in newborns that is fatal without intravenous feeding or intestinal transplant.

A Vanderbilt University-led research team has identified protein “signatures” of genetic mutations that drive colorectal cancer, the nation’s second leading cause of cancer deaths after lung cancer.