Department of Biochemistry Archive — Page 5 of 10

Black-and-white yin-yang symbol with two contrasting comma-shaped halves and a dot in each half.
February 14, 2019

The yin and yang of cell signaling

Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

Illustration of two robotic grippers suspended above separate conveyor belts carrying rows of small boxes.
January 17, 2019

Signals from the “conveyor belt”

Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.

Blue toggle switch between red “ON” and black “OFF” labels.
January 17, 2019

DNA’s on/off switch

DNA-binding “switches” represent a fundamentally new method of communication between DNA-processing enzymes, Vanderbilt researchers propose.

Portrait of Katherine Rothamel with long brown hair, wearing a dark top, in an indoor setting.
October 25, 2018

Rothamel selected as Vanderbilt Prize Student Scholar

Katherine Rothamel, a PhD student in the Department of Biochemistry at Vanderbilt University School of Medicine, has been selected as the 2017 Vanderbilt Prize Student Scholar.

Glowing white DNA double helix against a blue background patterned with electronic circuit traces and scattered light effects.
August 30, 2018

Energetic gene switch

New findings link flux through glycolysis, which produces cellular energy, with transcription and gene expression via histone modification.

Portrait of a smiling bald man wearing a striped collared shirt against a mottled brown background.
August 23, 2018

Enzyme helps build motor that drives neuron death

Vanderbilt scientists have discovered a signaling mechanism that tells neurons to die, findings that could lead to new treatments for neurodegenerative diseases.