Mental Health Archive — Page 1 of 13

A. Compared to healthy individuals, psychosis subtype 1 demonstrated significantly larger surface area across the cortex and larger basal ganglia volumes. B. Compared to healthy individuals, psychosis subtype 2 demonstrated widespread lower surface area and cortical thickness, and smaller subcortical volumes. (Hill, L.D., et al. Subtyping psychotic disorders using a data-driven approach reveals divergent cortical and cellular signatures. Mol Psychiatry (2026). https://doi.org/10.1038/s41380-026-03774-2. Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0/. Rights and Permissions: https://tinyurl.com/2e9nxeah.)
August 27, 2026

Brain scan method may improve diagnosis, treatment of psychosis

The study suggests that heterogeneity, or the wide range of symptoms, treatment responses and long-term outcomes observed in patients with various forms of psychosis, may reflect separate illness mechanisms and developmental pathways.

August 18, 2026

Could GLP-1s help treat opioid use disorder? Vanderbilt Health study now enrolling

The study, Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder (TAB), is a double-blind, randomized, placebo-controlled trial conducted through the National Institute on Drug Abuse’s Clinical Trials Network.

July 7, 2026

Duke Health’s Jonathan Posner named System Psychiatrist-in-Chief and Chair of the Department of Psychiatry and Behavioral Sciences

“I have been struck by the quality of the faculty, the strength of the institution, and the genuine warmth of the Vanderbilt community. I am thrilled to be joining Vanderbilt Health and look forward to the work ahead.”

(iStock)
July 3, 2026

Vanderbilt Center for Cognitive Medicine seeks participants for trial evaluating Alzheimer’s disease-related psychosis treatment

The ADEPT-4 study evaluates KarXT, an oral medication that may reduce hallucinations and delusions.

June 3, 2026

Study finds link between neighborhood opportunity and mental health-related hospitalizations in youths

Opportunity is measured by the Child Opportunity Index 3.0, a publicly available, multidimensional metric that captures neighborhood conditions that influence children’s health, like education, housing, access to healthy food, environment and societal factors.

(iStock)
May 18, 2026

Study finds benefit in genotype-guided care for depression

Genetic variants known to slow or speed metabolism of drugs for depression and anxiety disorders are very common.